Effect Of Methanolic Leaves Extract of Telfairia occidentalis on 2,4-Dinitrophenylhydrazine Induced Anaemic Rats
نویسندگان
چکیده
Anaemia constitutes a serious health problem in many tropical countries including Nigeria because of the high prevalence malaria and other parasitic infections which possibly leads to decrease hemoglobin. Fluted pumpkin has been reported be very good building constituents blood also replacing them. This study investigated effects methanolic leaves extract fluted on some hematological parameters 2, 4-dinitrophenylhydrazine-induced anaemic rats. Thirty Wister rats both sexes were separated into five groups six each. Group 1 serves as normal control, while 2-5 induced with anaemia using 40mg/kg body weight 2,4- dinitrophenylhydrazine. 2 negative control without treatment, group 3 given 20 mg/kg (b.w) standard hematinic drug astymin, 4 5 administered 200 400 w/w Telfairia occidentals respectively. All fed grower’s mash water ad libitum for 21 days. The sacrificed samples collected analysis. analysis was done methods. result this demonstrated that oral administration 400mg/kg increased haematological under investigation. A significant (p<0.05) increase haematinic activity observed 5, it concluded could effective ameliorating anaemia.
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ژورنال
عنوان ژورنال: UMYU Journal of Microbiology Research
سال: 2022
ISSN: ['2616-0668']
DOI: https://doi.org/10.47430/ujmr.2271.011